Mucopolysaccharidosis Type I (MPS I) is a rare inherited lysosomal storage disorder caused by a deficiency in the enzyme alpha-L-iduronidase. The lack of this enzyme results in the buildup of glycosaminoglycans (GAGs) within cells, disrupting normal function and causing progressive damage to various organ systems. The disease manifests with a broad

Pheochromocytomas and Paragangliomas (PPGLs) are rare neuroendocrine tumors that are frequently underdiagnosed. These tumors arise from chromaffin cells—either within the adrenal medulla in the case of pheochromocytomas or from extra-adrenal paraganglia in the case of paragangliomas. A hallmark of these tumors is the excess secretion of catechola

Triple Negative Breast Cancer (TNBC) is a highly aggressive and distinct breast cancer subtype, defined by the lack of estrogen receptors (ER), progesterone receptors (PR), and human epidermal growth factor receptor 2 (HER2). This receptor absence renders many standard breast cancer treatments ineffective, creating a critical demand for new, target